{"id":1642,"date":"2018-08-05T12:40:58","date_gmt":"2018-08-05T10:40:58","guid":{"rendered":"https:\/\/www.federicovotadesign.it\/nobilbio\/?p=1642"},"modified":"2025-07-24T12:43:48","modified_gmt":"2025-07-24T10:43:48","slug":"permanent-wettability-of-a-novel-nanoengineered-clinically-available-hyaluronan%e2%80%90coated-dental-implant","status":"publish","type":"post","link":"https:\/\/www.federicovotadesign.it\/nobilbio\/permanent-wettability-of-a-novel-nanoengineered-clinically-available-hyaluronan%e2%80%90coated-dental-implant\/","title":{"rendered":"Permanent wettability of a novel, nanoengineered, clinically available, hyaluronan\u2010coated dental implant"},"content":{"rendered":"<p><strong>Abstract<\/strong><br \/>\nThe objectives of this study are to evaluate long\u2010term wettability of novel surfaceengineered, clinically available dental implants, featuring a surface nanolayer of covalently linked hyaluronan, and to confirm the relationships between wetting properties and surface nanostructure and microstructure. Wettability measurements were performed on clinically available hyaluronan\u2010coated Grade 4 titanium implants, packaged and sterile, that is, in the \u201con the shelf\u201d condition, after 1 year from production. Wetting properties were measured by the Wilhelmy plate method. Analysis of the surface structure and chemistry was perfomed by X\u2010ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and energy\u2010dispersive X\u2010ray (EDX) analysis, atomic force microscopy (AFM), and \u03b6\u2010potential measurement, either on implants or disks or plates subjected to the same surface\u2010engineering process. Results show that hydrophilicity and ensuing capillary rise of the hyaluronan\u2010coated implant surface is unaffected by aging and dry storage. Chemical analysis of the implant surface by XPS and evaluation of the \u03b6 potential indicate that hyaluronan chemistry and not that of titanium dictates interfacial properties. Comparison between XPS versus EDX and SEM versus AFM data confirm that the thickness of the hyaluronan surface layer is within the nanometer range. Data show that nanoengineering of the implant surface<br \/>\nby linking of the hydrophilic hyaluronan molecule endows tested titanium implants by permanent wettability, without need of wet storage as presently performed to keep long\u2010term hydrophilic implant surfaces. From an analytical point of view, the introduction in routine clinical practice of nanoengineered implant surfaces requires upgrading of analytical methods to the nanoscale.<\/p>\n<p><strong>Keywords<\/strong><br \/>\ndental implants, hydrophilicity, wettability<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-content\/uploads\/2025\/07\/Morra_et_al-2018-Clinical_and_Experimental_Dental_Research.pdf\" target=\"_blank\" rel=\"noopener\">SCARICA LA PUBBLICAZIONE COMPLETA<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract The objectives of this study are to evaluate long\u2010term [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1644,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-1642","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pubblicazioni"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/posts\/1642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/comments?post=1642"}],"version-history":[{"count":1,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/posts\/1642\/revisions"}],"predecessor-version":[{"id":1645,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/posts\/1642\/revisions\/1645"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/media\/1644"}],"wp:attachment":[{"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/media?parent=1642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/categories?post=1642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.federicovotadesign.it\/nobilbio\/wp-json\/wp\/v2\/tags?post=1642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}